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Placental tissue, once considered biologic waste following delivery, is a pristine newly formed extracellular matrix (ECM) that protects and supports fetal development. This tissue represents an untainted extracellular matrix—essentially a neomatrix.
Placental tissue broadly includes:
Amnion (fetus-facing layer): Thinner yet more compact extracellular matrix
Chorion (maternal-facing layer): Slightly thicker but less compact matrix
Both layers are constituted primarily of collagen fibers (Types I, III, IV, and V) along with other ECM proteins including laminin, fibronectin, proteoglycans, and hyaluronic acid.
Donated tissues are collected from fully consented mothers undergoing full-term C-sections
1: Each donor is screened according to standards required by the U.S. Food and Drug Administration (FDA) and the American Association of Tissue Banks (AATB)
2: Products undergo a validated terminal sterilization process
3: Tissue is obtained through FDA-regulated and accredited recovery organizations
Amnio Defend™ Placental-Derived Allograft (361 HCT/Ps) is intended as a natural biologic wound covering or skin substitute for cutaneous wounds. Use by qualified healthcare professionals is for application in physician office, outpatient, or inpatient settings.